The 10 States With the Highest STD Rates – Latest CDC Data

New data reveals that the epidemic of sexually transmitted diseases in America may be showing early signs of stabilizing after years of steady increases. According to the latest figures from 2023, the rates of certain STDs have begun to level off or slightly decrease compared...

New data reveals that the epidemic of sexually transmitted diseases in America may be showing early signs of stabilizing after years of steady increases. According to the latest figures from 2023, the rates of certain STDs have begun to level off or slightly decrease compared to previous years.

National Overview: The Big Three STDs

More than 2.3 million cases of chlamydia, gonorrhea, and primary and secondary syphilis were reported in the United States in 2023. While these numbers remain alarmingly high, they represent a modest improvement from previous peaks.

Chlamydia continues to be the most commonly reported STD, with approximately 1.65 million cases diagnosed in 2023. Gonorrhea follows with 601,319 reported cases, showing a decline from the pandemic-era peak of 677,769 cases in 2020. Primary and secondary syphilis affected more than 53,000 people in 2023.

top 10 sti states

The Syphilis Resurgence Raises Alarms

The data shows a significant resurgence of syphilis, a disease once nearly eliminated in the United States. Between 2014 and 2023, primary and secondary syphilis cases increased by 165%, despite showing signs of leveling off in the most recent year.

South Dakota experienced the most dramatic increase in syphilis over the past five years, with rates jumping by more than 1,460% between 2018 and 2023. Other states with significant increases include Montana (up 554%), Delaware (up 461%), and Iowa (up 281%).

Unlike chlamydia and gonorrhea, which show more consistent regional patterns, syphilis presents a more complex picture. While the South has the highest overall burden, individual states across different regions have experienced concerning outbreaks.

Signs of Progress Amid Ongoing Challenges

The data shows some encouraging signs. Gonorrhea cases have declined from their pandemic-era peak, down from 677,769 cases in 2020 to 601,319 in 2023. This reverses what had been a generally upward trend since 2014.

However, public health experts caution that it’s too early to declare victory. The overall STD burden remains at crisis levels, with more than 2.3 million Americans diagnosed with chlamydia, gonorrhea, or syphilis in 2023 alone.

Regional Variations Tell an Important Story

The Northeast consistently shows lower STD rates compared to other regions, with an average gonorrhea rate of 112.8 per 100,000 and a chlamydia rate of 359.8 per 100,000. This stands in stark contrast to the South, which has gonorrhea rates 75% higher (196.7 per 100,000) and chlamydia rates 53% higher (550.4 per 100,000).

The Midwest and West fall between these extremes, with the Midwest showing slightly higher gonorrhea rates (158.2 per 100,000) compared to the West (138.1 per 100,000), while chlamydia rates are fairly similar between these regions (463.2 and 430.7 per 100,000 respectively).

Addressing the Crisis: A Public Health Imperative

The data suggests that increased awareness, testing, and treatment efforts may be beginning to yield results in some areas. However, sustained commitment is necessary to address the ongoing epidemic.

For individuals, regular STD screening remains one of the most important tools for prevention and early treatment. All sexually active individuals, regardless of perceived risk or geographic location, should consider STD testing as a routine part of their healthcare.

As we analyze these latest statistics, it’s clear that while there are encouraging signs of progress in some areas, STDs remain a significant public health challenge requiring continued attention, resources, and commitment at national, state, and local levels.

The Top 10 States with the Highest STD Rates

new york

10. New York

Total STD Rate: 808.8 per 100,000

Change From 2022: 5.6% increase

Chlamydia Rate: 558.4 per 100,000

Gonorrhea Rate: 235.6 per 100,000

Syphilis Rate (cumulative): 14.8 per 100,000

Resources: New York State Department of Health | STD Testing in New York

Arkansas

9. Arkansas

Total STD Rate: 802.2 per 100,000

Change From 2022: 5.0% decrease

Chlamydia Rate: 579.6 per 100,000

Gonorrhea Rate: 193.4 per 100,000

Syphilis Rate (cumulative): 29.2 per 100,000

Resources: Arkansas Department of Health | STD Testing in Arkansas

South Carolina

8. South Carolina

Total STD Rate: 851.8 per 100,000

Change From 2022: 11.6% decrease

Chlamydia Rate: 612.1 per 100,000

Gonorrhea Rate: 222.4 per 100,000

Syphilis Rate (cumulative): 17.3 per 100,000

Resources: South Carolina Department of Health and Human Services | STD Testing in South Carolina

North Carolina

7. North Carolina

Total STD Rate: 871.0 per 100,000

Change From 2022: 0.6% decrease

Chlamydia Rate: 607.9 per 100,000

Gonorrhea Rate: 243.2 per 100,000

Syphilis Rate (cumulative): 19.9 per 100,000

Resources: North Carolina Department of Health and Human Services | STD Testing in North Carolina

Alabama

6. Alabama

Total STD Rate: 906.6 per 100,000

Change From 2022: 1.0% increase

Chlamydia Rate: 651.1 per 100,000

Gonorrhea Rate: 226.9 per 100,000

Syphilis Rate (cumulative): 28.6 per 100,000

Resources: Alabama Department of Public Health | STD Testing in Alabama

5. Georgia

Total STD Rate: 941.2 per 100,000

Change From 2022: 3.4% decrease

Chlamydia Rate: 646.4 per 100,000

Gonorrhea Rate: 274.8 per 100,000

Syphilis Rate (cumulative): 20.0 per 100,000

Resources: Georgia Department of Public Health | STD Testing in Georgia

South Dakota

4. South Dakota

Total STD Rate: 858.3 per 100,000

Change From 2022: 13.2% decrease

Chlamydia Rate: 531.6 per 100,000

Gonorrhea Rate: 253.3 per 100,000

Syphilis Rate (cumulative): 73.4 per 100,000

Resources: South Dakota Department of Health | STD Testing in South Dakota

Alaska

3. Alaska

Total STD Rate: 1,063.4 per 100,000

Total STD Rate: 1,031.1 per 100,000

Change From 2022: 3.1% decrease

Chlamydia Rate: 697.7 per 100,000

Gonorrhea Rate: 310.9 per 100,000

Syphilis Rate (cumulative): 22.5 per 100,000

Resources: New York State Department of Health | STD Testing in Alaska

Mississippi

2. Mississippi

Total STD Rate: 982.1 per 100,000

Change From 2022: 17.1% decrease

Chlamydia Rate: 700.9 per 100,000

Gonorrhea Rate: 251.1 per 100,000

Syphilis Rate (cumulative): 30.1 per 100,000

Resources: Mississippi State Department of Health | STD Testing in Mississippi

Louisiana

1. Louisiana

Total STD Rate: 1,106.9 per 100,000

Change From 2022: 3.1% decrease

Chlamydia Rate: 792.4 per 100,000

Gonorrhea Rate: 288.4 per 100,000

Syphilis Rate (cumulative): 26.1 per 100,000

Resources: Louisiana Department of Health | STD Testing in Louisiana

Sources:

CDC, Sexually Transmitted Infections Surveillance, 2023. (Nov ’24) https://www.cdc.gov/sti-statistics/annual/index.html

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